Systems biology

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Scientific American is the world's premier magazine of scientific discovery and technological innovation for the general public. Readers turn to it for a deep understanding of how science and technology can influence human affairs and illuminate the natural world.

Kreb Cycle on Jay Holser's The Great Respiratory vol. 18. Metabolism_18

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The Citric Acid Cycle

The ability of oleaginous fungi to produce lipids for biofuels remains untapped, in part due to a lack of genetic information required to engineer industrial strains. Zhuet al. present the genome of R. toruloides, and identify transcriptomic and proteomic changes associated with lipid production.

TJ.In biochemistry, the pentose phosphate pathway (also called the phosphogluconate pathway and the hexose monophosphate shunt) is a metabolic pathway parallel to glycolysis that generates NADPH and pentoses (5-carbon sugars) as well as Ribose 5-phosphate, a precursor for the synthesis of nucleotides. While it does involve oxidation of glucose, its primary role is anabolic rather than catabolic. There are two distinct phases in the pathway. The first is the oxidative phase, in which NADPH…

Pentose Phosphate Pathways - Pathway II

ENTHALPY, ENTROPY, & GIBB’S FREE ENERGY

In determining the fate of pyruvate after glycolysis, two questions need to be asked; 1. Is there oxygen present i.e. aerobic conditions? 2. Are there any mitochondria present to facilitate TCA…