The Cell Cycle: Phases of Cell Division and Growth👇 📎The cell cycle is a series of events that lead to cell division and replication. It consists of four major phases: G1, S, G2, and M, along with a resting phase known as G0. The cell cycle ensures that cells grow, replicate their DNA, and divide into two daughter cells with identical genetic information. 📌G1 Phase (Gap 1): G1 is the first phase of the cell cycle, occurring after the previous cell division. During this phase, the cell grows...
Developmental mitochondrial complex I activity determines lifespan👇 📎Many human diseases are associated with aberrant mitochondrial function. 📎The authors show that developmental but not adulthood complex I (CI) depletion reduces lifespan, increases stress sensitivity and alters metabolic homeostasis despite comparable reduction in CI activity but, depletion of CI in adulthood only is not sufficient to reduce lifespan in Drosophila. 📎They also demonstrate that CI dysfunction in early deve...
Mechanism of neuroinflammation protection by astrocytes👇 📎The role of astrocytes in controlling neuroinflammation is not fully understood. Astrocytes are critical in maintaining homeostasis in the central nervous system (CNS), but how they regulate inflammation during neuroinflammatory conditions remains unclear. Recent research has shed light on the molecular mechanisms by which astrocytes can modulate neuroinflammation. 📎Role of BATF2 in Neuroinflammation The researchers found that the ba...
