E.histolytica has two stages which are trophozoite and cysts. The cysts are marked by the presence of a chromatoid body, and chromatin clumping along with several karyosomes. The trophozoite is makred by a single karyosome and ingested RBC. The infection can be treated with iodoquinol, paromomycin, metronidazole, dehydroemetine, and combinations.
Entamoeba histolytica (ameba). Infection occurs by ingestion of infective cysts from feces, hands, food, fomites, and flies. Excystation occurs in the small intestine; asexual multiplication and trophozoites in the large intestine. Infective cysts are released through the feces. Diagnosis by recovery/identification of cysts or trophozoites from feces or intestinal mucosa. Image from CDC via Pinterest, information from Medical Parasitology, A Self-Instructional Text.